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PF-CBP1 hydrochloride
CAS No. 2070014-93-4
PF-CBP1 hydrochloride ( PF CBP1 hydrochloride )
Catalog No. M13218 CAS No. 2070014-93-4
A potent, highly selective inhibitor of the CBP and p300 bromodomains with IC50 of 125 nM and 363 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NamePF-CBP1 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, highly selective inhibitor of the CBP and p300 bromodomains with IC50 of 125 nM and 363 nM, respectively.
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DescriptionA potent, highly selective inhibitor of the CBP and p300 bromodomains with IC50 of 125 nM and 363 nM, respectively; displays >100-fold selectivity for the bromodomain of CBP over those of BRD4 and a panel of other proteins; reduces the expression of inflammatory cytokines by LPS-stimulated primary macrophages, also suppresses the expression of RGS4 in primary cortical neurons.
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SynonymsPF CBP1 hydrochloride
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number2070014-93-4
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Formula Weight525.08
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Molecular FormulaC29H37ClN4O3
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 34 mg/mL
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SMILESCCCOC1=CC=C(C=C1)CCC2=NC3=CC(C4=C(C)ON=C4C)=CC=C3N2CCN5CCOCC5.[H]Cl
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Chemical Name4-(2-(5-(3,5-dimethylisoxazol-4-yl)-2-(4-propoxyphenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chekler EL, et al. Chem Biol. 2015 Dec 17;22(12):1588-96.
molnova catalog
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